Clonilla's offspring
Gödöllő 16th of Janary 2007.

 The first cloned Hungarian mouse, Clonilla is given birth 8 healthy offspring. (1. picture) She takes care them carefully. This event shows that she able to be matured, fertilized and give birth as a "normal" other female mouse. In the last month the research group, leaded by András Dinnyés has created four healthy SCNT mice.

1.picture: Clonilla and her pupps

Our goals to produce SCNT mice from different donor cell types, like genetically modified ones. Further, we would like to clone rabbit. The research group is working in the ABC which is belong to FVM, and the experiments were financed by Wellcome Trust, EU 6., NKTH and OTKA grants.(See more details below.)

The first Hungarian colone mouse is born
Gödöllő, Monday, 6th of November 2006.

In Hungary the first sucsessful cloned animal from somatic cell was produced by the Genetic Reprograming Group.
     The project was supported by EU, Wellcome Trust and Hungarian state subsidization like FVM, OTKA and NKTH grants. The effect of the three years project was to produce a cloned mouse from cumulus cell by replace an oocyte nucleus with an other mouse cumulus’ nucleus. After birth the new first Hungarian clone mice was named “Clonilla”. (See below, the black pup)

 
picture: Clonilla (black pup), the first Hungarian cloned mouse.

       This result is an important step for the system of the ART (Assisted Reproductive Technology) which can produce transgenic mice, rabbits and other species, and this procedure can be a big help to develop the clinical research of several human disease.    
Some different genes knock out cloned animals can be use for the object for the research which can help to find the reason of some genetic background of human disease. The research group is planning to produce clone rabbit till 2008 and after that might be focus on produce clone rat, swine and cattle, and further this technology can play a role to save endangered species.     
 

short video about Clonilla

The project was supported by :

The  Agricultural Biotechnology Center (ABC) ,controlled by  Ministry of Agriculture and Rural Development (MARD)
http://www.fvm.gov.hu

Wellcome Trust

The Wellcome Trust is the most diverse biomedical research charity in the world, spending about Ł450 million every year both in the UK and internationally to support and promote research that will improve the health of humans and animals. The Trust was established under the will of Sir Henry Wellcome, and is funded from a private endowment, which is managed with long-term stability and growth in mind.
http://www.wellcome.ac.uk

    EU 6. program

Marie Curie Excellence Grants (EXT) give promising researchers the opportunity to set up or develop their own research teams in Europe. The action helps to enhance the careers of these promising researchers by helping them to attain research independence more rapidly. With the help of  the EXT grant, the researcher will be able to carry out an ambitious leading-edge research project of particular importance to Europe.
    http://www.cordis.lu/mariecurie-actions/ext/home.html

OTKA
    http://www.otka.hu

    NKTH
http://www.nkth.gov.hu

 

Other news

July 2006: The European Commission and the Agricultural Biotechnology Center have signed the new EU FP6 Marie Curie Research Training Network (RTN) project.  Title of the project: “Training Network Of Novel Animal Models For Medical Purposes” (CLONET)

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